Nonarticular foot and ankle pain is best
approached with a consideration of the region affected: the forefoot, midfoot,
or hindfoot [see Figure 3].

Figure 3. Causes of Foot Pain. In the anterior
foot, hallux valgus may cause diffuse pain, whereas Morton neuroma is usually
localized. Tarsal tunnel syndrome causes paresthesias over the medial and
plantar aspect. Plantar fasciitis and Achilles tendinitis are common causes of
posterior foot pain.
Hallux valgus is the leading cause of forefoot
pain. It is a common deformity that causes pain because of direct pressure over
the first metatarsophalangeal joint resulting from footwear or because of
pressure over the lateral toe joints caused by crowding of the toes. In the
lateral toes, hammer toe (i.e., plantar flexion of the proximal interphalangeal
joint), claw toe (i.e., plantar flexion of the proximal and distal
interphalangeal joints), or mallet toe (i.e., isolated flexion contracture of
the distal interphalangeal joint) may be associated with a dorsiflexion
contracture of the metatarsophalangeal joint. Initial treatment of these
problems should begin with adequate footwear that allows ample width for the
metatarsal heads, individualized orthoses, and surgical correction (reserved
for patients with persistent pain). Morton neuroma is an entrapment neuropathy
of the interdigital nerve, with or without an associated plantar neuroma, that
is most commonly seen between the third and fourth metatarsal heads. Patients
report pain and paresthesia radiating into the affected toes; tenderness
between the metatarsal heads that reproduces the described symptoms will also
be found. Orthoses to decrease pressure in the area, local glucocorticoid
injection, or surgical excision of the neuroma may be needed to relieve
symptoms.
Midfoot pain is usually the result of
deformities of the arch of the foot or arthritic changes of the midfoot joints.
Patients with a cavus foot deformity, peripheral neuropathies, or previous
ligamentous injuries from sprains may be predisposed to excessive stresses on
the midfoot and early osteoarthritic changes. Tarsal tunnel syndrome is caused
by entrapment of the posterior tibial nerve under the flexor retinaculum on the
medial side of the ankle. Symptoms of pain and paresthesia over the plantar and
distal foot and toes are usually present, and the Tinel sign may be positive.
Tarsal tunnel syndrome is much less common and more difficult to diagnose than
carpal tunnel syndrome in the wrist. Treatment consists of splinting and
NSAIDs. Local glucocorticoid injection and surgical decompression are not as
predictably successful as in carpal tunnel syndrome.
Plantar fasciitis is one of the most common
causes of hindfoot pain. Patients report pain over the plantar aspect of the
heel and midfoot that worsens with walking. Localized tenderness along the
plantar fascia or at the insertion of the calcaneus is helpful in diagnosis.
Plantar fasciitis is associated with obesity, pes planus, and activities that
stress the plantar fascia and may also be seen in systemic arthropathies such
as ankylosing spondylitis and Reiter syndrome. Although radiographic spurs in
the affected area are common, they may also be seen in asymptomatic persons and
are therefore not diagnostic. Orthoses, heel cord stretching exercises, NSAIDs,
and local glucocorticoid injection may be helpful, whereas surgery is seldom
indicated. Posterior heel pain is usually caused by Achilles tendinitis or by
bursitis of the bursae that lie superficial or deep to the insertion of the
Achilles tendon at the calcaneus. Although usually associated with
overactivity, Achilles tendinitis may also be part of ankylosing spondylitis
and Reiter syndrome. NSAIDs and orthoses designed to reduce stress on the
tendon (e.g., heel lifts) are usually helpful. In most cases, glucocorticoid
injections in the Achilles tendon area should be avoided because of the risk of
tendon rupture.
1. Sheon RP, Moskowitz
RW, Goldberg VM: Soft Tissue Rheumatic Pain: Recognition, Management,
Prevention, 3rd ed. Lea &Febiger, Philadelphia, 1996
2. Eck JC, Hodges
SD, Humphreys SC: Whiplash: a review of a commonly misunderstood injury. Am J
Med 110:651, 2001
3. Cassidy JD,
Carroll LJ, Cote P, et al: Effect of eliminating compensation for pain and
suffering on the outcome of insurance claims for whiplash injury. N Engl J Med
342:1179, 2000
4. Barnsley L,
Lord SM, Wallis BJ, et al: Lack of effect of intraarticular corticosteroids for
chronic pain in the cervical zygapophyseal joints. N Engl J Med 330:1047, 1994
5. Lord SM,
Barnsley L, Wallis BJ, et al: Percutaneous radio frequency neurotomy for
chronic cervical zygoapophyseal-joint pain. N Engl J Med 335:1721, 1996
6. Hoving JL,
Koes BW, de Vet HC, et al: Manual therapy, physical therapy, or continued care
by a general practitioner for patients with neck pain: a randomized, controlled
trial. Ann Intern Med 136:713, 2002
7. Swezey RL:
Conservative treatment of cervical radiculopathy. J Clin Rheumatol 5:65, 1999
8. Deyo RA,
Weinstein JN: Low back pain. N Engl J Med 344:363, 2001
9. Andersson GB:
Epidemiological features of chronic low-back pain. Lancet 354:581, 1999
10. Lee P, Helewa
A, Goldsmith CH, et al: Low back pain: prevalence and risk factors in an
industrial setting. J Rheumatol 28:346, 2001
11. Von Korff M,
Moore JC: Stepped care for back pain: activating approaches for primary care.
Ann Intern Med 134:911, 2001
12. Deyo RA, Diehl
AK, Rosenthal M: How many days of bed rest for acute low back pain? A
randomized clinical trial. N Engl J Med 315:1064, 1986
13. Malmivaara A,
Hakkinen U, Aro T, et al: The treatment of acute low back pain: bed rest,
exercises, or ordinary activity? N Engl J Med 332:351, 1995
14. Vroomen PC, de
Krom MC, Wilmink JT, et al: Lack of effectiveness of bed rest for sciatica. N
Engl J Med 340:418, 1999
15. Andersson GBJ,
Lucente T, Davis AM, et al: A comparison of osteopathic spinal manipulation
with standard care for patients with low back pain. N Engl J Med 341:1426, 1999
16. Cherkin DC,
Deyo RA, Battie M, et al: A comparison of physical therapy, chiropractic
manipulation, and provision of an educational booklet for the treatment of
patients with low back pain. N Engl J Med 339:1021, 1998
17. Moffett JK,
Torgerson D, Bell-Syer S, et al: Randomised controlled trial of exercise for
low back pain: clinical outcomes, costs, and preferences. BMJ 319:279, 1999
18. Daltroy LH,
Iverson JD, Larson MG, et al: A controlled trial of an educational program to
prevent low back injuries. N Engl J Med 337:322, 1997
19. Jensen MC,
Brant-Zawadzki MN, Obuchowski N, et al: Magnetic resonance imaging of the
lumbar spine in people without back pain. N Engl J Med 331:69, 1994
20. Deen HG:
Diagnosis and management of lumbar disk disease. Mayo Clin Proc 71:283, 1996
21. Salerno SM,
Browning R, Jackson JL: The effect of antidepressant treatment on chronic back
pain: a meta-analysis. Arch Intern Med 162:19, 2002
22. Carette S,
Marcoux S, Truchon R, et al: A controlled trial of corticosteroid injections
into facet joints for chronic low back pain. N Engl J Med 325:1002, 1991
23. Mannion AF,
Muntener M, Taimela S, et al: Comparison of three active therapies for chronic
low back pain: results of a randomized clinical trial with one-year follow-up.
Rheumatology (Oxford) 40:772, 2001
24. Cherkin DC,
Eisenberg D, Sherman KJ, et al: Randomized trial comparing traditional Chinese
medical acupuncture, therapeutic massage, and self-care education for chronic
low back pain. Arch Intern Med 161:1081, 2001
25. Arbit E,
Pannullo S: Lumbar stenosis: a clinical review. Clin Orthop 384:137, 2001
26. Saint-Louis
LA: Lumbar spinal stenosis assessment with computed tomography, magnetic
resonance imaging, and myelography. Clin Orthop 384:122, 2001
27. Simotas AC:
Nonoperative treatment for lumbar spinal stenosis. Clin Orthop 384:153, 2001
28. Amundsen T,
Weber H, Nordal HJ, et al: Lumbar spinal stenosis: conservative or surgical
management? A prospective 10-year study. Spine 25:1424, 2000
29. Steinfeld R,
Valente RM, Stuart MJ: A commonsense approach to shoulder problems. Mayo Clin
Proc 74:785, 1999
30. Green S,
Buchbinder R, Glazier R, et al: Systematic review of randomised controlled
trials of interventions for painful shoulder: selection criteria, outcome
assessment, and efficacy. BMJ 316:354, 1998
31. van der Windt DA,
Koes BW, Deville W, et al: Effectiveness of corticosteroid injections versus
physiotherapy for treatment of painful stiff shoulder in primary care:
randomised trial. BMJ 317:1292, 1998
32. Ebenbichler
GR, Erdogmus CB, Resch KL, et al: Ultrasound therapy for calcific tendinitis of
the shoulder. N Engl J Med 340:1533, 1999
33. Dahan TH,
Fortin L, Pelletier M, et al: Double blind randomized clinical trial examining
the efficacy of bupivacaine suprascapular nerve blocks in frozen shoulder. J
Rheumatol 27:1464, 2000
34. Wise CM: Chest
wall syndromes. Curr Opin Rheumatol 6:197, 1994
35. Hay EM,
Paterson SM, Lewis M, et al: Pragmatic randomised controlled trial of local
corticosteroid injection and naproxen for treatment of lateral epicondylitis of
elbow in primary care. BMF 319:964, 1999
36. Smidt N, van
der Windt DA, Assendelft WJ, et al: Corticosteroid injections, physiotherapy,
or a wait-and-see policy for lateral epicondylitis: a randomised controlled
trial. Lancet 359:657, 2002
37. Laupland KB,
Davies HD: Olecranon septic bursitis managed in an ambulatory setting. The
Calgary Home Parenteral Therapy Program Study Group. Clin Invest Med 24:171,
2001
38. Dawson D:
Entrapment neuropathies of the upper extremities. N Engl J Med 329:2013, 1993
39. Atroshi I,
Gummesson C, Johnsson R, et al: Prevalence of carpal tunnel syndrome in a
general population. JAMA 282:153, 1999
40. D'Arcy CA,
McGee S: The rational clinical examination: does this patient have carpal
tunnel syndrome? JAMA 283:3110, 2000
41. O'Gardaigh D,
Merry P: Corticosteroid injection for the treatment of carpal tunnel syndrome.
Ann Rheum Dis 59:918, 2000
42. Katz JN,
Losina E, Amick BC 3rd, et al: Predictors of outcomes of carpal tunnel release.
Arthritis Rheum 44:1184, 2001
43. Kapoor A,
Sibbitt W: Contractures in diabetes mellitus: the syndrome of limited joint
mobility. Semin Arthritis Rheum 18:168, 1989
44. Bird PA,
Oakley SP, Shnier R, et al: Prospective evaluation of magnetic resonance
imaging and physical examination findings in patients with greater trochanteric
pain syndrome. Arthritis Rheum 44:2138, 2001
45. Bernstein J:
Patellar disorders. J Clin Rheumatol 5:90, 1999
46. O'Keeffe ST:
Restless legs syndrome: a review. Arch Intern Med 156:243, 1996
47. Goldenberg DL:
Fibromyalgia syndrome a decade later: what have we learned? Arch Intern Med 159:777,
1999
48. Crofford LJ,
Clauw DJ: Fibromyalgia: where are we a decade after the American College of
Rheumatology classification criteria were developed? Arthritis Rheum 46:1136,
2002
49. O'Malley PG,
Balden E, Tomkins G, et al: Treatment of fibromyalgia with antidepressants: a
meta-analysis. J Gen Intern Med 15:659, 2000
50. Hadhazy VA,
Ezzo J, Creamer P, et al: Mind-body therapies for the treatment of
fibromyalgia: a systematic review. J Rheumatol 27:2911, 2000